Evaluation of chitosan microparticles containing curcumin and crosslinked with sodium tripolyphosphate produced by spray drying
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چکیده
منابع مشابه
Alginate microparticles produced by spray-drying for oral insulin delivery
In spite of the prevalence of subcutaneous injections for insulin administration, there are several concerns associated with this mode of administration including injection anxiety, pain, cost, infection, and as a result an overall decrease in patient compliance (Khafagy 2007). This has prompted researchers to search for alternative delivery methods including transdermal, nasal, pulmonary, rect...
متن کاملEvaluation of physiochemical properties of curcumin-loaded Chitosan Tripolyphosphate Nanoparticles
Introduction: Curcumin is a water-insoluble agent with some anticancer and antimicrobial effects; while, solubility is essential for a medicine to reach target cells. This study set out to use chitosan tripolyphosphate nanoparticles (CTN) for making curcumin water-soluble, and delivering the required dosage of it to target cells. ...
متن کاملStability tests of 5-Aminosalicylic acid containing solutions and chitosan-Ca-alginate microparticles prepared by spray-drying
5-ASA is widely used for its local effects in the treatment of inflammatory bowel diseases (Loftus, 2004). Because of the 4-aminophenol structure and antioxidative properties it is considered as a light, temperature and oxygen sensitive drug and its major degradation products are well established (Jensen, 1992). As a zwitter ion, dominantly anionic, 5-ASA has low aqueous solubility and it is po...
متن کاملSodium Tripolyphosphate (TPP) Crosslinked Chitosan Membranes and Application in Humic Acid Removal
Macroor micro-porous chitosan membranes have been utilized as adsorptive membrane for the removal of metal ions, organic macromolecules or bioseparation of protein mixtures. The removal or separation mechanism is not based on physical size retention but based on the high adsorption capability of chitosan to the target solutes. For this purpose, it is important that large macro or micro pores an...
متن کاملEffect of manufacturing parameters on the characteristics of vitamin C encapsulated tripolyphosphate-chitosan microspheres prepared by spray-drying.
To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentration and volume of 1% w/v TPP solution) had a significant influence on the charac...
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ژورنال
عنوان ژورنال: Química Nova
سال: 2012
ISSN: 0100-4042
DOI: 10.1590/s0100-40422012000600011